Baylor College of Medicine Detects T Cells that Triggers Lifelong Anticancer Response in Mice

Scientists at Baylor College of Medicine have discovered a crucial regulator of the anticancer immune response that could point to the development of new approaches to fight cancer. The research showed that transferring the regulatory T cells (Tregs) without SRC-3 to animals carrying breast cancer tumors resulted in long-term elimination of the tumor without negative side effects.

SRC-3 is not only highly expressed in all human cancers and plays a role in cancer growth, but it is also strongly expressed in Tregs that regulate the immune response to cancer. It had also been suspected that SRC-3 plays a role in regulating Treg function.