Colossal Biosciences Achieves iPSC Breakthrough for Woolly Mammoth Project

Colossal Biosciences, the pioneering de-extinction company, announces a groundbreaking achievement: their Woolly Mammoth team has achieved a global-first iPSC (induced pluripotent stem cells) breakthrough. This milestone, a key early goal of the mammoth project, supports the feasibility of future multiplex ex utero mammoth gestation. iPSC cells, capable of indefinite propagation and generating all cell types, hold immense potential beyond de-extinction, including cell development studies, cell therapy, drug screening, synthetic embryos, and more. This breakthrough offers invaluable opportunities for studying cold adaptation traits in Woolly Mammoths, such as woolly hair growth and fat storage, using multiplex-edited and differentiated iPSCs in cellular and organoid models.